Anti-CD47 [OX-101]
Product Sizes
1 mg
AB00570-1-1-BT-1MG
About this Product
- SKU:
- AB00570-1-1-BT
- Additional Names:
- IAP; OX101; MRC OX-101; MRC OX101; leukocyte surface antigen CD47; integrin-associated protein; intergin associated protein
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- OX-101
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- OX-101 was prepared by immunizing BALB/c mice with biotinylated rat thymocytes - this antibody was selected from a number of antibodies raised by the immunogen.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- OX-101 binds specifically to CD47 and has been shown to compete with OX-41 for binding . CD47 acts as an adhesionn receptor for THBS1 on platelets and is involved in the modulation of integrins (signalling). Acts as a SIRPA receptor - SIRPA binding prevents maturation of immature dentritic cells and and inhibits cytokine production by mature dendritic cells. Possibly involved in changes to membran
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00570-1.1-BT
