Anti-Glycoprotein D of HSV [E317]
Product Sizes
500 ug
AB00442-10-7-BT-500UG
About this Product
- SKU:
- AB00442-10-7-BT
- Additional Names:
- Envelope glycoprotein D; gD
- Application:
- Block/Inhibit/Neutralise, ELISA, Immunoprecipitation
- Buffer:
- PBS
- translate.label.attr.clone:
- E317
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- Herpes simplex virus 1.
- Purification:
- Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds specifically to the glycoprotein D of HSV. The epitope core structure maps to the external surface of gD, corresponding to the binding sites of two receptors, herpesvirus entry mediator (HVEM) and nectin-1, which mediate HSV infection. E317 directly recognizes the gD-nectin-1 interface and occludes the HVEM contact site of gD to block its binding to either receptor. The binding
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00442-10.7-BT
