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Antibodies

Anti-CD28 [E18]

Product Sizes
200 ug
Was £463.00 £440.00
AB00286-1-6-200UG
About this Product
SKU:
AB00286-1-6
Additional Names:
TP44; T-cell-specific surface glycoprotein CD28; TP44
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry, Immunohistochemistry, Surface Plasmon Resonance
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
E18
Clonality:
Recombinant Monoclonal
Extra Details:
This is a directly produced Fab fragment permitting comparison to the Fc Silentâ„¢ variant in dissection of the mechanism underlying the differential effect of full length antibody and Fab-fragment in previous studies (c.f. Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
CD28
Purification:
Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
Recognises mouse CD28 at the interaction site with B7 and blocks binding to B7. Intact antibody (but not Fab fragments) trigger Treg proliferation in pro-inflammatory settings, and protect from graft-versus-host disease.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies