Anti-Citrullinated collagen type II [ACC4]
Product Sizes
200 ug
AB00224-1-1-200UG
About this Product
- SKU:
- AB00224-1-1
- Additional Names:
- ACPA; CII; Col II; COL2A1; citrullinated CII; citrullinated Col II; Col C II; citrullinated proteins; antibodies against citrullinated proteins; Collagen alpha-1(II) chain; Alpha-1 type II collagen; C1 epitope of citrullinated collagen type II as an a-chain peptide
- Application:
- ELISA, IHC-Frozen
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- ACC4
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The original antibody was generated by immunizing a DBA/1 or (B10.Q xDBA/1) F1 mouse with calcium-dependent peptidyl arginine deiminase (PAD4) treated helical CII peptides containing T and B cell epitopes emulsified in CFA.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds the citrullinated C1 epitope (amino acids 359 - 369 : ARGLTGRPGDA) as an A Alpha-chain peptide of the collagen type II and also shows binding affinity for the cyclic citrullinated filaggrin peptide. C1 peptide contains two arginines which are post translationally converted to citrulline. ACC4 was found to recognize the first citrulline at position 360. This antibody does not cr
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00224-1.1
