Anti-desmoglein-3 [PVB28]
Product Sizes
500 ug
AB00158-1-1-BT-500UG
About this Product
- SKU:
- AB00158-1-1-BT
- Additional Names:
- Pemphigus Vulgaris Ag; 130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6; DSG3; CDHF6
- Application:
- ELISA, Immunofluorescence
- Buffer:
- PBS
- translate.label.attr.clone:
- PVB28
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- Made by immortalizing IgG-expressing B cells from Pemphigus vulgaris (PV) patients.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody specifically recognizes a conformational epitope in the EC2 domain of human desmoglein-3 (DSG This antibody was isolated as a human IgG4 from a patient with mucocutaneous pemphigus vulgaris and uses the VH4-39*07, D6-13*01, JH4*02, VL3-15*01and JL2*01. This antibody has in vitro and in vivo pathogenic activity, as assessed in a keratinocyte dissociation assay and by the formation of
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00158-1.1-BT
