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Antibodies

Anti-erbB-2 (Her-2/neu) [4D5-8 (trastuzumab)]

Product Sizes
200 ug
Was £463.00 £440.00
AB00103-2-0-200UG
About this Product
SKU:
AB00103-2-0
Additional Names:
CD340; Metastatic lymph node gene 19 protein (MLN 19); Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; p185HER2; EGFR
Application:
ELISA, Flow Cytometry, Immunohistochemistry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
4D5-8 (trastuzumab)
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
Isotype:
IgG2a
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies