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Antibodies

SARS-CoV-2 Neutralizing Antibodies Detection Kit

Product Sizes
1 X 96 Tests
£1008.00
90-7005-96T
About this Product
SKU:
90-7005
Extra Details:
Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory; gastrointestinal; hepatic and central nervous system of human and many other wild animals. Recently; a new severe acute respiratory syndrome β-coronavirus called SARS-CoV-2 has emerged; which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19). SARS-CoV-2 contains 4 structural proteins; including Envelope (E); Membrane (M); Nucleocapsid (N) and Spike (S); which is a transmembrane protein; composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD); which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells; causing mainly infection of human respiratory cells.The SARS-CoV-2 Neutralizing Antibodies Detection Kit contains key reagents required to test the presence of functional neutralizing antibodies against SARS-CoV-2 present in the serum or plasma. It is an easy and fast alternative to the classical neutralization assay using Vero E6 cells. This Detection Kit is based on a colorimetric reaction; which measures the binding of the RBD of the Spike S protein from SARS-CoV-2 to its human receptor ACE2. The presence of neutralizing / blocking antibodies in the samples are detected by reduction of signal indicating the inhibition of the Spike-ACE2 binding.
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to the Manual
Supplier:
Abeomics
Type:
Antibodies:In Vivo Antibodies