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Antibodies

Anti-Tocilizumab Antibody (Clone: 6C10); mAb; Mouse

Product Sizes
40 µg
£525.00
45-1123-40UG
About this Product
SKU:
45-1123
Additional Names:
Mouse monoclonal to Actemra
translate.label.attr.clone:
6C10
Clonality:
Monoclonal
Extra Details:
Tocilizumab also known as atlizumab; is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration. It has a high affinity to IL-6R and blocks the IL-6 signaling by preventing the formation of the IL-6/IL-6R complex. Tocilizumab is used for the trea„¢ent of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis; a severe form of arthritis in children. Anti-Tocilizumab Antibody (6C10); mAb; Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Tocilizumab.
Format:
Purified
Host:
Mouse
Immunogen:
Tocilizumab
Isotype:
Mouse IgG2b
Purification:
Protein A chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibody is stable in lyophilized form if stored at -20[o]C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8[o]C. For long term storage; aliquot and store at -20[o]C or below. Avoid repeated freezing and thawing cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure-2 : ELISA binding of Anti-Tocilizumab Antibody (6C10) with Tocilizumab. While the antibody does not recognize the human IgG (data not shown).Coating antigen: Tocilizumab; 1 µg/ml. Anti-Tocilizumab Antibody (6C10) dilutions start from 1;000 ng/ml. EC50= 1.837 ng/ml.
Figure-3 : Standard curve of Tocilizumab Sandwich ELISA. The Tocilizumab Sandwich ELISA assay is developed by using Anti- Tocilizumab Antibody (14B10); mAb; Mouse (Abeomics 45-1122) and Anti-Tocilizumab Antibody (6C10); mAb; Mouse (Abeomics 45-1123) as the capture and detection antibodies; respectively In this ELISA assay; Anti-Tocilizumab Antibody (6C10); mAb; Mouse was labeled with Biotin. The sensitivity is less than 100 pg/ml.
Figure-3 : Standard curve of Tocilizumab Sandwich ELISA. The Tocilizumab Sandwich ELISA assay is developed by using Anti- Tocilizumab Antibody (14B10); mAb; Mouse (Abeomics 45-1122) and Anti-Tocilizumab Antibody (6C10); mAb; Mouse (Abeomics 45-1123) as the capture and detection antibodies; respectively In this ELISA assay; Anti-Tocilizumab Antibody (6C10); mAb; Mouse was labeled with Biotin. The sensitivity is less than 100 pg/ml.