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Antibodies

Biotinylated Rabbit Monoclonal Antibody to Bevacizumab/Avastin (Clone : 46E3)

Product Sizes
40 µg
£594.00
45-1117-40UG
About this Product
SKU:
45-1117
translate.label.attr.clone:
46E3
Clonality:
Monoclonal
Conjugate:
Biotin
Extra Details:
Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with colon cancer; lung cancer; glioblastoma; renal-cell carcinoma; and age-related macular degeneration. As an angiogenesis inhibitor; Bevacizumab blocks angiogenesis by inhibiting vascular endothelial growth factor A (VEGF-A).
Format:
Purified
Host:
Rabbit
Immunogen:
Bevacizumab
Isotype:
Rabbit IgG
Purification:
Protein A chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibody is stable in lyophilized form if stored at -20[o]C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8[o]C. For long term storage; aliquot and store at -20[o]C or below. Avoid repeated freezing and thawing cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure-2 : ELISA Blocking of Biotin conjugated Bevacizumab Antibody (Clone: 46E3) with Vascular Endothelial Growth Factor 165 (VEGF 165); Coating antigen: Bevacizumab at 0.3 µg/ml; Anti-Bevacizumab Antibody (Clone: 46E3)final concentration: 8 ng/ml; VEGF 165 dilution start from 20 µg/ml; IC50= 46.16 ng/ml.
Figure-3 : Standard curve of Bevacizumab Sandwich ELISA; The Bevacizumab Sandwich ELISA assay is developed by using Bevacizumab Antibody (Clone: 30E1)and Biotin conjugated Bevacizumab Antibody (Clone: 46E3) as the capture and detection antibodies respectively; The sensitivity of detecting Bevacizumab is up to 20 pg/ml.
Figure-3 : Standard curve of Bevacizumab Sandwich ELISA; The Bevacizumab Sandwich ELISA assay is developed by using Bevacizumab Antibody (Clone: 30E1)and Biotin conjugated Bevacizumab Antibody (Clone: 46E3) as the capture and detection antibodies respectively; The sensitivity of detecting Bevacizumab is up to 20 pg/ml.