Anti-PD-L1 Rabbit Monoclonal Antibody (Clone:IHC411)-Ready to Use
Product Sizes
7 ml
£592.00
44-1070-7ML
About this Product
- SKU:
- 44-1070
- translate.label.attr.clone:
- IHC411
- Clonality:
- Monoclonal
- Extra Details:
- Programmed Death-Ligand 1 (PD-L1); also known as CD274 or B7 Homolog 1 (B7-H1); is a transmembrane protein involved in suppressing the immune system and rendering tumor cells resistant to CD8+ T cell-mediated lysis through binding of the Programmed Death-1 (PD-1) receptor. Overexpression of PD-L1 may allow cancer cells to evade the actions of the host immune system. In renal cell carcinoma; upregulation of PD-L1 has been linked to increased tumor aggressiveness and risk of death; and; in ovarian cancer; higher expression of this protein has lead to significantly poorer prognosis. PD-L1 has also been linked to systemic lupus erythematosus and cutaneous melanoma. When considered in adjunct with CD8+ tumor-infiltrating lymphocyte density; expression levels of PD-L1 may be a useful predictor of multiple cancer types; including stage III non-small cell lung cancer; hormone receptor negative breast cancer; and sentinel lymph node melanoma.""
- Host:
- Rabbit
- Immunogen:
- Recombinant Human PD-L1
- Isotype:
- Rabbit IgG
- Purification:
- Protein A/G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2[o]C - 8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
