Anti-PD-1 Monoclonal Antibody (Clone:IHC001)-Ready to Use
Product Sizes
7 ml
£533.00
44-1068-7ML
About this Product
- SKU:
- 44-1068
- Additional Names:
- PDCD1||PD1
- translate.label.attr.clone:
- IHC001
- Clonality:
- Monoclonal
- Extra Details:
- Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T-cell regulators; expressed as a co-receptor on the surface of activated T-cells; B-cells; and macrophages. New studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to anti-tumor immunity; as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6; PD-1 is expressed by fewer B cells and has therefore been considered a more specific marker for angioimmunoblastic T-cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer; including non€“small-cell lung cancer; melanoma; and renal-cell cancer.""
- Host:
- Mouse
- Immunogen:
- Recombinant human His-PD1
- Isotype:
- Mouse IgG2b
- Purification:
- Protein A/G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2[o]C - 8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
