Anti-HSP40; YDJ1 Monoclonal Antibody (Clone : 1G10.H8) - APC
Product Sizes
100 µg
£625.00
42-1335-100UG
About this Product
- SKU:
- 42-1335
- Additional Names:
- YDJ1||MAS5||YNL064C||N2418||YNL2418C
- translate.label.attr.clone:
- 1G10.H8
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- Human HSP40/DnaJ proteins comprise a large protein family; members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of HSP40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding; type II does not. Members of the HSP40/DnaJ family play diverse roles in many cellular processes; such as folding; translocation; degradation and assembly of multi-protein complexes. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins. The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip; Hop and HSP90 which leads to protein folding; or components of protein degradation machinery CHIP and BAG-1.
- Host:
- Mouse
- Immunogen:
- Full length protein yeast HSP40 (YDJ1)
- Isotype:
- Mouse IgG1 Kappa
- Purification:
- Protein G Purified
- Reactivities:
- Yeast/Fungi
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
