Anti-Caspase-3 Polyclonal Antibody
Product Sizes
100 μg/vial
£785.00
39-2098-100UG
About this Product
- SKU:
- 39-2098
- Additional Names:
- Caspase-3; CASP-3; 3.4.22.56; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12; CASP3; CPP32
- Clonality:
- Polyclonal
- Extra Details:
- Caspase 3 is a caspase protein which interacts with Survivin; XIAP; CFLAR; Caspase 8; HCLS1; Deleted in Colorectal Cancer; TRAF3 and GroEL. This gene which is located at 4q35 encodes a protein that is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 6; 7; and 9; and the protein itself is processed by caspases 8; 9; and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein; which is associated with neuronal death in Alzheimer's disease.
- Host:
- Rabbit
- Isotype:
- Rabbit IgG
- Purification:
- Immunogen affinity purified.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
