Anti-GAD67 Polyclonal Antibody
Product Sizes
100 μg/vial
£785.00
39-2047-100UG
About this Product
- SKU:
- 39-2047
- Additional Names:
- Glutamate decarboxylase 1; 4.1.1.15; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform; GAD1; GAD; GAD67
- Clonality:
- Polyclonal
- Extra Details:
- Glutamic acid decarboxylase(GAD) catalyses the conversion of L-glutamic acid to the inhibitory neurotransmitter gamma-aminobutyric acid(GABA). Two forms of human GAD; GAD65 and GAD67; are encoded by two separate genes. Human GAD65 cDNA encodes a Mr 65;000 polypeptide; with 585 amino acid residues; whereas human GAD67 encodes a Mr 67;000 polypeptide; with 594 amino acid residues. GAD67 gene consists of 16 exons; spread over more than 45 kb of genomic DNA. The GAD67 gene contains an additional exon(exon 0) that together with part of exon 1; specifies the 5' untranslated region of GAD67 mRNA. Human GAD67 shows 65% identity to GAD65 and is located in 2q31. GAD67 may play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.
- Host:
- Rabbit
- Isotype:
- Rabbit IgG
- Purification:
- Immunogen affinity purified.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
