Anti-CD40L Polyclonal Antibody
Product Sizes
100 μg/vial
£785.00
39-2038-100UG
About this Product
- SKU:
- 39-2038
- Additional Names:
- CD40 ligand; CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD154; CD40 ligand; membrane form; CD40 ligand; soluble form; CD40LG; CD40L;
- Clonality:
- Polyclonal
- Extra Details:
- CD40 ligand(CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta; and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons; is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1; and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation; its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb /IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence at the N-terminus of human CD40L(47-65aa HRRLDKIEDERNLHEDFVF); different from the related mouse sequence by three amino acids; rat sequence by four amino acids.
- Isotype:
- Rabbit IgG
- Purification:
- Immunogen affinity purified.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
