Anti-Angiopoietin 2 Polyclonal Antibody
Product Sizes
100 μg/vial
£785.00
39-2016-100UG
About this Product
- SKU:
- 39-2016
- Additional Names:
- Angiopoietin-2; ANG-2; ANGPT2
- Clonality:
- Polyclonal
- Extra Details:
- Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium; by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60% homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding; and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches; ovary; placenta and uterus.
- Format:
- Lyophilized
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminus of human Angiopoietin 2(454-468aa NLNGMYYPQRQNTNK).
- Isotype:
- Rabbit IgG
- Purification:
- Immunogen affinity purified.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
