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Antibodies

Anti-Alkaline Phosphatase Polyclonal Antibody

Product Sizes
100 μg/vial
£785.00
39-2015-100UG
About this Product
SKU:
39-2015
Additional Names:
Alkaline phosphatase; tissue-nonspecific isozyme; AP-TNAP; TNSALP; 3.1.3.1 ; Alkaline phosphatase liver/bone/kidney isozyme; ALPL
Clonality:
Polyclonal
Extra Details:
Alkaline phosphatase(ALPL) removes phosphate groups from the 5' end of DNA and RNA; and from proteins; at high pH. Most mammals have 4 different isozymes: placental; placental like; intestinal and non tissue specific(found in liver; kidney and bone). Tissues with particularly high concentrations of ALP include the liver; bile ducts; placenta; and bone. ALPL is the alkaline phosphatase of skin fibroblasts;the tissue-nonspecific type; and that it is active toward millimolar concentrations of the putative natural substrates phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP). ALPL gene exists in single copy in the haploid genome and is composed of 12 exons distributed over more than 50 kb.Damaged or diseased tissue releases enzymes into the blood; so serum ALP measurements can be abnormal in many conditions; including bone disease and liver disease.
Format:
Lyophilized
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Alkaline Phosphatase(31-45aa DQAQETLKYALELQK); different from the related mouse and rat sequences by three amino acids.
Isotype:
Rabbit IgG
Purification:
Immunogen affinity purified.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg