Anti-MBD2 Polyclonal Antibody
Product Sizes
100 μg/vial
£785.00
39-2005-100UG
About this Product
- SKU:
- 39-2005
- Additional Names:
- Methyl-CpG-binding domain protein 2; Demethylase; DMTase; Methyl-CpG-binding protein MBD2; MBD2
- Clonality:
- Polyclonal
- Extra Details:
- Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene. It is mapped to 18q21.2. Human proteins MECP2; MBD1; MBD2; MBD3; and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD). Each of these proteins; with the exception of MBD3; is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that this protein functions as a demethylase to activate transcription; as DNA methylation causes gene silencing.
- Format:
- Lyophilized
- Host:
- Rabbit
- Immunogen:
- E.coli-derived human MBD2 recombinant protein (Position: W159-A411). Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2.
- Isotype:
- Rabbit IgG
- Purification:
- Immunogen affinity purified.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
