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Antibodies

Anti-CD4; Mouse (T-Cell Marker) Monoclonal Antibody(Clone: GK1.5)

Product Sizes
20 µg
£397.00
36-3823-20UG
100 µg
£716.00
36-3823-100UG
About this Product
SKU:
36-3823
Additional Names:
CD4 (L3T4); CD4; CD4+ Lymphocyte deficiency; included; Leu3; Ly-4; Lymphocyte antigen CD4; p55; T cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
translate.label.attr.clone:
GK1.5
Clonality:
Monoclonal
Extra Details:
CD4 is a member of the Ig superfamily; primarily expressed on most thymocytes; a subset of T cells; and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase; lck. CD4 is expressed by the majority of thymocytes; most helper T cells; a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens; including cytolysis; proliferation; allogeneic B cell help; and release of lymphokines.
Host:
Rat
Immunogen:
Mouse CTL clone V4
Isotype:
Rat IgG2b; kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody