Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Anti-HLA-Pan (MHC II) Monoclonal Antibody(Clone: rHLA-Pan/3475)

Product Sizes
20 µg
£397.00
36-3747-20UG
100 µg
£716.00
36-3747-100UG
About this Product
SKU:
36-3747
Additional Names:
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
translate.label.attr.clone:
rHLA-Pan/3475
Clonality:
Monoclonal
Extra Details:
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens; HLA-DP; -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36kDa) and a beta chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes; monocytes; macrophages; and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci; DR; DQ and DP; encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They; therefore; have a critical role in the initiation of the immune response.
Host:
Mouse
Immunogen:
Non-T; non-B human acute lymphoblastic leukemia REH6 cells
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: SDS-PAGE Analysis Purified HLA-Pan Mouse Recombinant Monoclonal Antibody (rHLA-Pan/3475). Confirmation of Purity and Integrity of Antibody.
Fig. 3: Flow Cytometric Analysis of Human Raji cells using HLA-Pan Mouse Recombinant Monoclonal Antibody (rHLA-Pan/3475)followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype control (Red).
Fig. 4: Immunofluorescence Analysis of Human Raji cells with HLA-Pan Mouse Recombinant Monoclonal Antibody (rHLA-Pan/3475) followed by goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red).
Fig. 4: Immunofluorescence Analysis of Human Raji cells with HLA-Pan Mouse Recombinant Monoclonal Antibody (rHLA-Pan/3475) followed by goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red).