Anti-Cytokeratin 7/17 Monoclonal Antibody(Clone: C-46)
Product Sizes
20 µg
£397.00
36-3734-20UG
100 µg
£716.00
36-3734-100UG
About this Product
- SKU:
- 36-3734
- Additional Names:
- CK-7; K2C7; Keratin 55K Type II Cytoskeletal; Keratin Simple Epithelial Type 1 K7; Keratin Type II Cytoskeletal 7; Krt2-7; KRT7; Sarcolectin; SCL; Type II Mesothelial Keratin K7; Type-II Keratin Kb7; CK17; K17; Keratin Type I Cytoskeletal 17; Keratin-17; KRT17; PCHC1
- translate.label.attr.clone:
- C-46
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes intermediate filament proteins (IFP's) of 55kDa and 46kDa; which are identified as cytokeratin 7 and Cytokeratin 17 respectively. On formalin-fixed; paraffin embedded sections; C-46 reacts with keratin 7 only. Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation; which is directly applicable to the characterization of malignant tumors. Cytokeratin 7 is a basic cytokeratin; which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Cytokeratin 7 is expressed in the epithelial cells of ovary; lung; and breast but not of colon; prostate; or gastrointestinal tract. Cytokeratin 17 is expressed in epithelial cells of various origins; such as bronchial epithelial cells and skin appendages. Cytokeratin 17 antibody marks basal cell differentiation.
- Host:
- Mouse
- Immunogen:
- Cytoskeletal preparation from HeLa cells (human cervical carcinoma cells)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
