Anti-Cdk1 / p34cdc2 Serine-Threonine Kinase Monoclonal Antibody(Clone: A17.1.1)
Product Sizes
20 µg
£397.00
36-3669-20UG
100 µg
£716.00
36-3669-100UG
About this Product
- SKU:
- 36-3669
- Additional Names:
- Cdc2; CDC28A; CDK1; CDKN1; CELL CYCLE CONTROLLER CDC2; Cell division control protein 2 homolog; Cell division cycle 2 G1 to S and G2 to M; Cell division protein kinase 1; Cyclin-dependent kinase 1; p34 Protein Kinase; P34CDC2
- Application:
- Immunoprecipitation
- translate.label.attr.clone:
- A17.1.1
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a 34kDa protein (cdk1); identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thoµght to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase; which is activated by cyclin; by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins.
- Host:
- Mouse
- Immunogen:
- C-Terminal 2/3rds of Xenopus cdc2 expressed in E.coli
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
