Anti-CD74 (B-Cell Marker) Monoclonal Antibody(Clone: CLIP/3127R)
Product Sizes
20 µg
£397.00
36-3652-20UG
100 µg
£716.00
36-3652-100UG
About this Product
- SKU:
- 36-3652
- Additional Names:
- CLIP; DHLAG; Gamma chain of class II antigens; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; HLADR-gamma (HLADG); Ia antigen-associated invariant chain; la-gamma; Major histocompatibility complex class II invariant chain; MHC HLA-DR gamma chain
- translate.label.attr.clone:
- CLIP/3127R
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of ~35kDa; identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells; such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage); macrophages; and monocytes; and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas; but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
- Host:
- Rabbit
- Immunogen:
- SU-DHL-4 lymphoma cells
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
