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Antibodies

Anti-CD34 (Hematopoietic Stem Cell & Endothelial Marker) Monoclonal Antibody(Clone: ICO-115)-CF488

Product Sizes
0.5 at 100 ml at µg/ml
£716.00
36-3587-0.5AT100MLATUG
About this Product
SKU:
36-3587
Additional Names:
Hematopoietic Progenitor Cell Antigen; HPCA1; Mucosialin
translate.label.attr.clone:
ICO-115
Clonality:
Monoclonal
Conjugate:
CF488
Extra Details:
This antibody recognizes a carbohydrate epitope on a single chain; transmembrane; heavily glycosylated protein of 90-120kDa; which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition; it is expressed by soft tissue tumors; such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally; it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposi's sarcoma; but shows low specificity.
Host:
Mouse
Immunogen:
Blast cells of a chronic myeloid leukemia patient
Isotype:
Mouse IgG1; kappa
Reactivities:
Human, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 4 to 8[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg