Anti-MUC16 / CA125 (Ovarian Carcinoma Marker) Monoclonal Antibody(Clone: 5E11)
Product Sizes
20 µg
£397.00
36-3568-20UG
100 µg
£716.00
36-3568-100UG
About this Product
- SKU:
- 36-3568
- Additional Names:
- CA125; Cancer antigen 125; MUC16; Mucin16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125
- translate.label.attr.clone:
- 5 E 11
- Clonality:
- Monoclonal
- Extra Details:
- The mucins are a family of highly glycosylated; secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large; secreted and cell surface glycoproteins crucial for adhesion modulation; signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4; Mucin 5 (AC and B); Mucins 6-8; Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125); encoded for by the gene MUC16; is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain; an extracellular domain and an amino terminal domain. Mucin 16; an ovarian cancer-associated antigen; is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
- Host:
- Mouse
- Immunogen:
- Enzymatically glycosylated fragment of human MUC16 recombinant protein
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
