Anti-CD22 / BL-CAM (B-Cell Marker) Monoclonal Antibody(Clone: RFB4)
Product Sizes
20 µg
£397.00
36-3548-20UG
100 µg
£716.00
36-3548-100UG
About this Product
- SKU:
- 36-3548
- Additional Names:
- B-lymphocyte cell adhesion molecule (BL-CAM); B-cell receptor CD22; CD22; Lectin 2; Lyb8; Sialic acid-binding Ig-like lectin 2 (Siglec-2); SIGLEC2; T-cell surface antigen Leu-14
- translate.label.attr.clone:
- RFB4
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 130-140kDa; identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny; CD22 is first expressed in the cytoplasm of pro-B and pre-B cells; and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells; CD22 is found highly expressed in follicular mantle and marginal zone B-cells; and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
- Host:
- Mouse
- Immunogen:
- Human tonsil lymphocytes.
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
