Anti-CD7 (T-Cell Leukemia Marker) Monoclonal Antibody(Clone: HuLy-m2)
Product Sizes
20 µg
£397.00
36-3506-20UG
100 µg
£716.00
36-3506-100UG
About this Product
- SKU:
- 36-3506
- Additional Names:
- GP40; Leu9; p41; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
- translate.label.attr.clone:
- HuLy-m2
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 40kDa; identified as CD7 (Workshop IV; Code T165). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes; and T cell leukemia. It is also found on natural killer cells; a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes; expression of adhesion molecules; cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
- Host:
- Mouse
- Immunogen:
- Human thymocytes
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
