Anti-CD5 (Mantle Cell Lymphoma Marker) Monoclonal Antibody(Clone: CD5/2419)
Product Sizes
20 µg
£397.00
36-3496-20UG
100 µg
£716.00
36-3496-100UG
About this Product
- SKU:
- 36-3496
- Additional Names:
- CD5 antigen (p56 62); LEU1; Ly12; LyA; Lymphocyte antigen T1/Leu-1; Lymphocyte glycoprotein T1/Leu1; T-cell surface glycoprotein CD5
- translate.label.attr.clone:
- CD5/2419
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a 67kDa transmembrane protein; which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes; the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells; e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL); mantle cell lymphoma; and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers; especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition; anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
- Host:
- Mouse
- Immunogen:
- Recombinant human CD5 protein fragment (around aa 269-366) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2c; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
