Anti-RCAS1 / Estrogen Receptor Binding Site Associated; Antigen 9 Monoclonal Antibody(Clone: CPTC-EBAG9-2)
Product Sizes
20 µg
£397.00
36-3485-20UG
100 µg
£716.00
36-3485-100UG
About this Product
- SKU:
- 36-3485
- Additional Names:
- BAG9; cancer associated surface antigen; cancer associated surface antigen RCAS1; EB9; estrogen receptor binding fragment associated gene 9; PDAF; receptor binding cancer antigen expressed on SiSo cells
- translate.label.attr.clone:
- CPTC-EBAG9-2
- Clonality:
- Monoclonal
- Extra Details:
- EBAG9; also known as RCAS1; is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers; including uterine; ovarian; and lung cancer cells; and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis; contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human EBAG9 protein
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
