Anti-CD1a / HTA1 (Mature Langerhans Cells Marker) Polyclonal Antibody
Product Sizes
20 µg
£397.00
36-3455-20UG
100 µg
£716.00
36-3455-100UG
About this Product
- SKU:
- 36-3455
- Additional Names:
- Cortical thymocyte antigen CD1A; Epidermal dendritic cell marker CD1a antibody; FCB6; HTA1; T cell surface antigen T6 / Leu 6; T-Cell Surface Glycoprotein CD1A
- Clonality:
- Polyclonal
- Extra Details:
- At least five CD1 genes (CD1a; b; c; d; and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein; expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X); extranodal histiocytic sarcoma; a subset of T-lymphoblastic lymphoma/leukemia; and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5; anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas; but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
- Host:
- Rabbit
- Immunogen:
- Recombinant human CD1a protein
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
