Anti-Sarcomeric Actinin Alpha 2 / ACTN2 Monoclonal Antibody(Clone: ACTN2/3293)
Product Sizes
20 µg
£397.00
36-3436-20UG
100 µg
£716.00
36-3436-100UG
About this Product
- SKU:
- 36-3436
- Additional Names:
- Actin binding protein; Alpha actinin skeletal muscle; isoform 2; CMD1AA; F-actin cross-linking protein
- translate.label.attr.clone:
- ACTN2/3293
- Clonality:
- Monoclonal
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins; including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells; the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions; where it is involved in binding actin to the membrane. In contrast; skeletal; cardiac; and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies; where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific; alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
- Host:
- Mouse
- Immunogen:
- A recombinant fragment (aa557-692) of human ACTN2 protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
