Anti-CD262 / DR5 Monoclonal Antibody(Clone: DR5/3381)
Product Sizes
20 µg
£397.00
36-3433-20UG
100 µg
£716.00
36-3433-100UG
About this Product
- SKU:
- 36-3433
- Additional Names:
- Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death receptor 5 (DR5); p53 regulated DNA damage inducible cell death receptor (killer); TNF related apoptosis inducing ligand
- translate.label.attr.clone:
- DR5/3381
- Clonality:
- Monoclonal
- Extra Details:
- Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors; designated TNF-alpha1 and TNF-alpha2; which are expressed on most cell types. TNF function is primarily mediated throµgh TNF-alpha1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes Fas antigen and CD40. TNF-alpha1 contains a cytoplasmic motif; termed the death domain ; that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors; including Fas; DR2 (or TRUNDD); DR3 (death receptor 3); DR4 and DR5. TRUNDD; DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor; designated decoy receptor (DcR1 or TRID); also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli.
- Host:
- Mouse
- Immunogen:
- Recombinant human DR5 protein fragment (around aa266-393) (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
