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Antibodies

Anti-Calnexin (Endoplasmic Reticulum Marker) Monoclonal Antibody(Clone: CANX/1543)

Product Sizes
20 µg
£397.00
36-3412-20UG
100 µg
£716.00
36-3412-100UG
About this Product
SKU:
36-3412
Additional Names:
Calnexin; CANX; CNX; IP90; Major histocompatibility complex class I antigen-binding protein p88; P90
translate.label.attr.clone:
CANX/1543
Clonality:
Monoclonal
Extra Details:
It recognizes a protein of 90kDa; which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds; amino-linked glycosylation and folding. To help proteins fold properly; the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding; endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins; facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Host:
Mouse
Immunogen:
Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Western Blot of Analysis of PANC1 and MCF-7 cell lysate using Calnexin Mouse Monoclonal Antibody (CANX/1543).
Fig. 3: SDS-PAGE Analysis Purified Calnexin Mouse Monoclonal Antibody (CANX/1543). Confirmation of Integrity and Purity of Antibody.
Fig. 4: Western Blot of Analysis of human Kidney lysate using Calnexin Mouse Monoclonal Antibody (CANX/1543).
Fig. 4: Western Blot of Analysis of human Kidney lysate using Calnexin Mouse Monoclonal Antibody (CANX/1543).
Fig. 5: Analysis of Protein Array containing more than 19;000 full-length human proteins using Calnexin Mouse Monoclonal Antibody (CANX/1543). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that a