Anti-B7-H4 (Immuno-Inhibitory Protein) Monoclonal Antibody(Clone: B7H4/1788)
Product Sizes
20 µg
£397.00
36-3399-20UG
100 µg
£716.00
36-3399-100UG
About this Product
- SKU:
- 36-3399
- Additional Names:
- B7 family member; H4; B7 homolog 4; B7 superfamily member 1; B7-H4; B7S1; Immune costimulatory protein B7-H4; T-cell costimulatory molecule B7x; V-set domain-containing T-cell activation inhibitor 1; VCTN1
- translate.label.attr.clone:
- B7H4/1788
- Clonality:
- Monoclonal
- Extra Details:
- T cell activation and immune function are regulated by the innate immune system throµgh positive and negative costimulatory proteins. One such protein; B7-H4 (B7-homolog 4); belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells; B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes; thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies; including ovarian and breast cancer; as its interaction with T cells suppresses tumor-associated immunity. Current research sµggests that; similar to Mucin 16 (CA-125); B7-H4 may be a useful biomarker for the early detection of ovarian cancer.
- Host:
- Mouse
- Immunogen:
- A recombinant fragment of human B7-H4 protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:4.jpg
