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Antibodies

Anti-Renal Cell Carcinoma (Carbonic Anhydrase IX) Monoclonal Antibody(Clone: CA9/2993R)

Product Sizes
20 µg
£397.00
36-3385-20UG
100 µg
£716.00
36-3385-100UG
About this Product
SKU:
36-3385
Additional Names:
CA-IX; CA9; CAIX; Carbonate dehydratase IX; Carbonic anhydrase 9; Carbonic anhydrase IX; Carbonic dehydratase; G250; Membrane antigen MN; P54/58N; pMW1; RCC-associated antigen G250; Renal cell carcinoma-associated antigen G250
translate.label.attr.clone:
CA9/2993R
Clonality:
Monoclonal
Extra Details:
Recognizes a glycoprotein of ~200kDa; identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants; such as the Lewis blood group antigens; epithelial membrane antigen; HMFG; and AB blood group antigens. In normal kidney; gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule; as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly; gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Host:
Rabbit
Immunogen:
Recombinant full-length human CA9 protein
Isotype:
Rabbit IgG
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg