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Antibodies

Anti-14-3-3E / Tryptophan 5-Monooxygenase Monoclonal Antibody(Clone: CPTC-YWHAE-1)

Product Sizes
20 µg
£397.00
36-3380-20UG
100 µg
£716.00
36-3380-100UG
About this Product
SKU:
36-3380
Additional Names:
MDS; epididymis luminal protein 2; mitochondrial import stimulation factor (MSF) L subunit; Mitochondrial import stimulation factor L subunit; MSF L; protein kinase C inhibitor protein-1
translate.label.attr.clone:
CPTC-YWHAE-1
Clonality:
Monoclonal
Extra Details:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners; usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases; RAF1 and IRS1 proteins; sµggesting its role in diverse biochemical activities related to signal transduction; such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
Host:
Mouse
Immunogen:
Recombinant human full-length YWHAE protein
Isotype:
Mouse IgG2a; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Western Blot Analysis of HEK293; PC-3 and A431 cell lysates using 14-3-3E Mouse Monoclonal Antibody (CPTC-YWHAE-1).
Fig. 3: SDS-PAGE Analysis Purified 14-3-3E Mouse Monoclonal Antibody (CPTC-YWHAE-1). Confirmation of Purity and Integrity of Antibody
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using 14-3-3E Mouse Monoclonal Antibody (CPTC-YWHAE-1). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using 14-3-3E Mouse Monoclonal Antibody (CPTC-YWHAE-1). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that