Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody(Clone: WT1/1434R)
Product Sizes
20 µg
£397.00
36-3377-20UG
100 µg
£716.00
36-3377-100UG
About this Product
- SKU:
- 36-3377
- Additional Names:
- WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1
- translate.label.attr.clone:
- WT1/1434R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a 47-55kDa-tumor suppressor protein; identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids; frequently found in subsets of sporadic Wilm's tumors.WT1; a sporadic and familial pediatric kidney tumor; is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1; a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium; and its expression has been sµggested as a marker for Wilm's tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells; malignant mesothelioma; ovarian carcinoma; gonadoblastoma; nephroblastoma; and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
- Host:
- Rabbit
- Immunogen:
- Recombinant human full-length WT1 protein
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
