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Antibodies

Anti-Ezrin / p81 Monoclonal Antibody(Clone: CPTC-Ezrin-1)

Product Sizes
20 µg
£397.00
36-3361-20UG
100 µg
£716.00
36-3361-100UG
About this Product
SKU:
36-3361
Additional Names:
Villin-2; CVIL; Epididymis secretory protein Li 105; EZR; p81; VIL2; Cytovillin; Cytovillin 2; HEL S 105; DKFZp762H157
translate.label.attr.clone:
CPTC-Ezrin-1
Clonality:
Monoclonal
Extra Details:
Ezrin; Moesin and Radixin belong to a family of highly homologous actin-associated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases; including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70% homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology; the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.
Host:
Mouse
Immunogen:
Recombinant human full-length Ezrin protein
Isotype:
Mouse IgG2b
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Formalin-fixed; paraffin-embedded human Prostate Carcinoma stained with Ezrin Mouse Monoclonal Antibody (CPTC-Ezrin-1).
Fig. 3: SDS-PAGE Analysis Purified Ezrin Mouse Monoclonal Antibody (CPTC-Ezrin-1). Confirmation of Purity and Integrity of Antibody
Fig. 4: Western Blot Analysis of SKBr-3; HeLa; HEK293; MCF-7 cell lysates using Ezrin Mouse Monoclonal Antibody (CPTC-Ezrin-1).
Fig. 4: Western Blot Analysis of SKBr-3; HeLa; HEK293; MCF-7 cell lysates using Ezrin Mouse Monoclonal Antibody (CPTC-Ezrin-1).
Fig. 5: Analysis of Protein Array containing more than 19;000 full-length human proteins using Ezrin / p81 Mouse Monoclonal Antibody (CPTC-Ezrin-1). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on