Anti-Vinculin (Marker of Age-related Macular Degeneration) Monoclonal Antibody(Clone: VCL/2573)
Product Sizes
20 µg
£397.00
36-3351-20UG
100 µg
£716.00
36-3351-100UG
About this Product
- SKU:
- 36-3351
- Additional Names:
- CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; VCL; VINC
- translate.label.attr.clone:
- VCL/2573
- Clonality:
- Monoclonal
- Extra Details:
- Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo; these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal; focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins; including Talin and -Actinin each contain Actin binding sites. Reportedly; vinculin is a potential plasma biomarker for Age-related Macular Degeneration (AMD). The early detection of AMD using novel plasma biomarkers with genetic modeling may enable timely treatment and vision preservation in the elderly.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 174-322) of human Vinculin (VCL) protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
