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Antibodies

Anti-Vinculin (Marker of Age-related Macular Degeneration) Monoclonal Antibody(Clone: VCL/2572)

Product Sizes
20 µg
£397.00
36-3350-20UG
100 µg
£716.00
36-3350-100UG
About this Product
SKU:
36-3350
Additional Names:
CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; VCL; VINC
translate.label.attr.clone:
VCL/2572
Clonality:
Monoclonal
Extra Details:
Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo; these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal; focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins; including Talin and -Actinin has been shown to link Actin to integrins in the plasma membrane throµgh interactions with the vinculin and Talin complex or by a direct interaction with integrin.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 174-322) of human Vinculin (VCL) protein (exact sequence is proprietary)
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: SDS-PAGE Analysis Purified VCL Mouse Monoclonal Antibody (VCL/2572). Confirmation of Integrity and Purity of Antibody.
Fig. 3: Western Blot Analysis of U-87 and THP-1 cell lysate using VCL Mouse Monoclonal Antibody (VCL/2572).
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using Vinculin Mouse Monoclonal Antibody (VCL/2572). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that ar
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using Vinculin Mouse Monoclonal Antibody (VCL/2572). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that ar