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Antibodies

Anti-Uroplakin 1B (Urothelial Differentiation Marker) Monoclonal Antibody(Clone: UPK1B/3273)

Product Sizes
20 µg
£397.00
36-3348-20UG
100 µg
£716.00
36-3348-100UG
About this Product
SKU:
36-3348
Additional Names:
Tetraspanin-20; Tspan-20; TSPAN20; UP1b; UPIb; UPK1B; Uroplakin-1b
translate.label.attr.clone:
UPK1B/3273
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a member of the transmembrane 4 superfamily; also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development; activation; growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology; possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane throµgh AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary)
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Fig. 1: Formalin-fixed; paraffin-embedded human Urothelial Carcinoma stained with Monospecific Mouse Monoclonal Antibody to Uroplakin 1B (UPK1B/3273).
Fig. 2: Formalin-fixed; paraffin-embedded human Urothelial Carcinoma stained with Monospecific Mouse Monoclonal Antibody to Uroplakin 1B (UPK1B/3273).
Fig. 3: Formalin-fixed; paraffin-embedded human Urothelial Carcinoma stained with Monospecific Mouse Monoclonal Antibody to Uroplakin 1B (UPK1B/3273).
Fig. 4: SDS-PAGE Analysis Purified Uroplakin 1B Mouse Monoclonal Antibody (UPK1B/3273). Confirmation of Purity and Integrity of Antibody.
Fig. 5: Analysis of Protein Array containing more than 19;000 full-length human proteins using Monospecific Mouse Monoclonal Antibody to Uroplakin 1B (UPK1B/3273). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signal