Anti-Ubiquitin (Autophagy Marker) Monoclonal Antibody(Clone: UBB/1748)
Product Sizes
20 µg
£397.00
36-3339-20UG
100 µg
£716.00
36-3339-100UG
About this Product
- SKU:
- 36-3339
- Additional Names:
- Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2
- translate.label.attr.clone:
- UBB/1748
- Clonality:
- Monoclonal
- Extra Details:
- Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process; it is first activated by forming a thiol-ester complex with the activation component E1; which is then transferred to ubiquitin-carrier protein E2; followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB; p53; cdc25A; Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression; differentiation; cell stress response; and apoptosis. Moreover; ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease; Lewy bodies seen in Parkinson's disease; and Pick bodies found in Pick's disease etc.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2c; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
