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Antibodies

Anti-Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Monoclonal Antibody(Clone: TYRP1/3284)

Product Sizes
20 µg
£397.00
36-3332-20UG
100 µg
£716.00
36-3332-100UG
About this Product
SKU:
36-3332
Additional Names:
5; 6 dihydroxyindole 2 carboxylic acid oxidase; 6-dihydroxyindole-2-carboxylic acid oxidase; Associated with iris pigmentation; CAS2; Catalase B (CATB); DHICA oxidase; Glycoprotein75 (GP75); Melanoma antigen gp75
translate.label.attr.clone:
TYRP1/3284
Clonality:
Monoclonal
Extra Details:
It reacts with a 75kDa melanocyte-specific gene product; identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma; normal melanocytes and nevi.Recent evidence sµggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Host:
Mouse
Immunogen:
A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)
Isotype:
Mouse IgG2b; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg