Anti-OX40 / CD134/ TNFRSF4 (Immuno-Oncology Target) Monoclonal Antibody(Clone: OX40/3108)
Product Sizes
20 µg
£397.00
36-3322-20UG
100 µg
£716.00
36-3322-100UG
About this Product
- SKU:
- 36-3322
- Additional Names:
- ACT35; CD134; Lymphoid activation antigen ACT35; OX40; TAX transcriptionally-activated glycoprotein 1 receptor; TNFRSF4 (Tumor necrosis factor receptor superfamily member 4)
- translate.label.attr.clone:
- OX40/3108
- Clonality:
- Monoclonal
- Extra Details:
- ThisMAb recognizes a protein of 43kDa; identified as OX40; which is also known as CD134.OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. It is expressed on activated T lymphocytes; hematopoietic precursor cells and fibroblasts. It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand/TNFSF4 that is expressed by antigen presenting cells. OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation; proliferation or apoptosis of normal and malignant lymphoid cells.OX40 is upregulated at the sites of inflammation; especially in case of multiple sclerosis and psoriatic lesions.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human OX40 (CD134) protein (around aa 59-205) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2c; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
