Anti-Complement 3d (C3d) (Acute Humoral Rejection Marker) Monoclonal Antibody(Clone: C3D/2891)
Product Sizes
20 µg
£397.00
36-3310-20UG
100 µg
£716.00
36-3310-100UG
About this Product
- SKU:
- 36-3310
- Additional Names:
- Acylation stimulating protein cleavage product; AHUS5; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement component C3; CPAMD1
- translate.label.attr.clone:
- C3D/2891
- Clonality:
- Monoclonal
- Extra Details:
- The complement component proteins; C2; C3; C4 and C5; are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors; C3aR; C1R and C5aR; induces proinflammatory events; such as cellular degranulation; smooth muscle contraction; arachidonic acid metabolism; cytokine release; leukocyte activation and cellular chemotaxis. C3d is a terminal degradation product of C3 that plays an important role in modulation of the adaptive immune response throµgh the interaction with complement receptor type 2 (CR2). CR2 is important in the switched-isotype; high-affinity and memory humoral immune responses to T-dependent foreign antigens; as well as in the development of the natural antibody repertoire. This pH- and ionic strength-dependent association of C3d with CR2 represents a link between innate and adaptive immunity.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human Complement C3 protein
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
