Anti-p53 Tumor Suppressor Protein Monoclonal Antibody(Clone: TP53/1799R)
Product Sizes
20 µg
£397.00
36-3300-20UG
100 µg
£716.00
36-3300-100UG
About this Product
- SKU:
- 36-3300
- Additional Names:
- Antigen NY-CO-13; BCC7; Cellular Tumor Antigen p53; LFS1; TP53; Transformation Related Protein 53 (TRP53); Tumor Protein p53; Tumor Suppressor p53
- translate.label.attr.clone:
- TP53/1799R
- Clonality:
- Monoclonal
- Extra Details:
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array; containing more than 19;000; full-length human proteins. Recognizes a 53kDa protein; which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth; replication; and apoptosis. It binds to MDM2; SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma; lung carcinoma; colorectal; and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors; including breast; ovarian; bladder; colon; lung; and melanoma.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human TP53 protein
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
