Anti-C1QB / Complement C1q B-Chain Monoclonal Antibody(Clone: C1QB/2961)
Product Sizes
20 µg
£397.00
36-3284-20UG
100 µg
£716.00
36-3284-100UG
About this Product
- SKU:
- 36-3284
- Additional Names:
- C1QB; Complement component 1 q subcomponent B chain; Complement component C1q B chain
- translate.label.attr.clone:
- C1QB/2961
- Clonality:
- Monoclonal
- Extra Details:
- C1q; a subcomponent of the classical complement pathway; is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B; while three of these subunits; designated C1q-A throµgh C1q-C; are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity; which may be antibody-dependent or independent. Macrophages are the primary source of C1q; while anti-inflammatory drµgs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
