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Antibodies

Anti-C1QA / Complement C1q A-Chain Monoclonal Antibody(Clone: C1QA/2956)

Product Sizes
20 µg
£397.00
36-3277-20UG
100 µg
£716.00
36-3277-100UG
About this Product
SKU:
36-3277
Additional Names:
Complement C1q subcomponent subunit A; Complement component 1 q subcomponent alpha polypeptide
translate.label.attr.clone:
C1QA/2956
Clonality:
Monoclonal
Extra Details:
C1q; a subcomponent of the classical complement pathway; is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B; while three of these subunits; designated C1q-A throµgh C1q-C; are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity; which may be antibody-dependent or independent. Macrophages are the primary source of C1q; while anti-inflammatory drµgs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 104-237) of human C1QA protein (exact sequence is proprietary)
Isotype:
Mouse IgG2b; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Formalin-fixed; paraffin-embedded human Liver stained with C1QA Mouse Monoclonal Antibody (C1QA/2956).
Fig. 3: SDS-PAGE Analysis Purified C1QA Mouse Monoclonal Antibody (C1QA/2956). Confirmation of Purity and Integrity of Antibody.
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using C1QA Mouse Monoclonal Antibody (C1QA/2956). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using C1QA Mouse Monoclonal Antibody (C1QA/2956). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array