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Antibodies

Anti-TLE1 (Synovial Sarcoma Marker) Monoclonal Antibody(Clone: TLE1/2085)

Product Sizes
20 µg
£397.00
36-3268-20UG
100 µg
£716.00
36-3268-100UG
About this Product
SKU:
36-3268
Additional Names:
Enhancer of split groucho 1 (ESG1); Enhancer of split groucho-like protein 1; GRG1; TLE1; Transducin like enhancer of split 1; Transducin-like enhancer protein 1
translate.label.attr.clone:
TLE1/2085
Clonality:
Monoclonal
Extra Details:
Key players in the Notch pathway are the TLE genes; which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis; segmentation and sex determination. Transducin-like enhancer protein1 (TLE1) is a protein that isencoded by theTLE1 gene and is involved in control of hematopoiesis; neuronal; and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
Host:
Mouse
Immunogen:
Recombinant fragment (aa 175-338) of human TLE1 (exact sequence is proprietary)
Isotype:
Mouse IgG2a; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: SDS-PAGE Analysis Purified TLE1 Mouse Monoclonal Antibody (TLE1/2085). Confirmation of Purity and Integrity of Antibody.
Fig. 3: Western Blot Analysis of human HeLa cell lysate using TLE1 Mouse Monoclonal Antibody (TLE1/2085).
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using TLE1 Mouse Monoclonal Antibody (TLE1/2085). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using TLE1 Mouse Monoclonal Antibody (TLE1/2085). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array