Anti-TIMP1 (Marker of Lymph Node Metastasis) Monoclonal Antibody(Clone: 2A5)
Product Sizes
20 µg
£397.00
36-3256-20UG
100 µg
£716.00
36-3256-100UG
About this Product
- SKU:
- 36-3256
- Additional Names:
- Collagenase inhibitor; EPO; Erythroid-Potentiating Activity (EPA); Fibroblast collagenase inhibitor; Human Collagenase Inhibitor (HCI); Metalloproteinase inhibitor 1; Tissue Inhibitor of Metalloproteinase 1 (TIMP1)
- translate.label.attr.clone:
- 2A5
- Clonality:
- Monoclonal
- Extra Details:
- TIMP-1; TIMP-2; TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1; -2; -3 and -4) complex with metalloproteinases such as collagenases; gelatinases and stromelysins; resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia; and in the formation; branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer; outperforming CEA. Additionally; TIMP1 studies have demonstrated its role in CRC tumorigenesis; as well as observing its overexpression in metastatic lymph nodes.
- Host:
- Mouse
- Immunogen:
- A synthetic peptide (aa 72-82) of human TIMP1 protein (FQALGDAADIR)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
